Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM205252'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM205252 (US9249125, 3) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4[nH]nc(C(=O)NCCN5CCOCC5)c4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C43H45N11O4/c1-27-9-12-29(13-10-27)54-37(26-36(52-54)43(2,3)4)48-42(56)47-33-15-16-35(31-8-6-5-7-30(31)33)58-38-17-18-45-41(49-38)46-28-11-14-34-32(25-28)39(51-50-34)40(55)44-19-20-53-21-23-57-24-22-53/h5-18,25-26H,19-24H2,1-4H3,(H,44,55)(H,50,51)(H,45,46,49)(H2,47,48,56)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the l...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
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