Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM205258'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM205258 (US9249125, 11) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5OCCOc5c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)cc1 Show InChI InChI=1S/C42H44N8O6/c1-42(2,3)37-27-38(50(48-37)29-9-11-30(12-10-29)53-23-20-49-18-21-52-22-19-49)46-41(51)45-33-13-15-34(32-7-5-4-6-31(32)33)56-39-16-17-43-40(47-39)44-28-8-14-35-36(26-28)55-25-24-54-35/h4-17,26-27H,18-25H2,1-3H3,(H,43,44,47)(H2,45,46,51)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the l...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair