Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM205270'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM205270 (US9249125, 23) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2cc(Nc3ccc4[nH]ncc4c3)ncn2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C36H33N9O2/c1-22-9-12-25(13-10-22)45-33(18-31(44-45)36(2,3)4)42-35(46)41-29-15-16-30(27-8-6-5-7-26(27)29)47-34-19-32(37-21-38-34)40-24-11-14-28-23(17-24)20-39-43-28/h5-21H,1-4H3,(H,39,43)(H,37,38,40)(H2,41,42,46)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the l...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
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