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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM205286'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM205286
PNG
(US9249125, 39)
Show SMILES COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2cc(Nc3ccc4[nH]ncc4c3)ncn2)c2ccccc12)C(C)C
Show InChI InChI=1S/C35H31N9O3/c1-21(2)30-17-33(44(43-30)24-9-11-25(46-3)12-10-24)41-35(45)40-29-14-15-31(27-7-5-4-6-26(27)29)47-34-18-32(36-20-37-34)39-23-8-13-28-22(16-23)19-38-42-28/h4-21H,1-3H3,(H,38,42)(H,36,37,39)(H2,40,41,45)
PDB
MMDB

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US Patent
n/an/a 10n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the l...


US Patent US9249125 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72QG
More data for this
Ligand-Target Pair