Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM205301'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM205301 (US9249125, 54) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5[nH]ncc5c4)n3)c3ccccc23)n(n1)-c1cccc(OCCN2CCOCC2)c1 Show InChI InChI=1S/C41H42N10O4/c1-41(2,3)36-25-37(51(49-36)29-7-6-8-30(24-29)54-22-19-50-17-20-53-21-18-50)46-40(52)45-34-13-14-35(32-10-5-4-9-31(32)34)55-38-15-16-42-39(47-38)44-28-11-12-33-27(23-28)26-43-48-33/h4-16,23-26H,17-22H2,1-3H3,(H,43,48)(H,42,44,47)(H2,45,46,52)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the l...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
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