Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM205317'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM205317 (US9249125, 70) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3cc(Nc4ccc5[nH]ncc5c4)ncn3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)cc1 Show InChI InChI=1S/C41H42N10O4/c1-41(2,3)36-23-38(51(49-36)29-9-11-30(12-10-29)54-21-18-50-16-19-53-20-17-50)47-40(52)46-34-14-15-35(32-7-5-4-6-31(32)34)55-39-24-37(42-26-43-39)45-28-8-13-33-27(22-28)25-44-48-33/h4-15,22-26H,16-21H2,1-3H3,(H,44,48)(H,42,43,45)(H2,46,47,52)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the l...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
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