Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM205321'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM205321 (US9249125, 74) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5n(CCN6CCOCC6)ncc5c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)cc1 Show InChI InChI=1S/C47H53N11O5/c1-47(2,3)42-31-43(58(54-42)35-9-11-36(12-10-35)62-29-24-56-22-27-61-28-23-56)52-46(59)51-39-13-15-41(38-7-5-4-6-37(38)39)63-44-16-17-48-45(53-44)50-34-8-14-40-33(30-34)32-49-57(40)19-18-55-20-25-60-26-21-55/h4-17,30-32H,18-29H2,1-3H3,(H,48,50,53)(H2,51,52,59)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the l...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
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