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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM205322'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM205322
PNG
(US9249125, 75)
Show SMILES Cc1nc2cc(Nc3nccc(Oc4ccc(NC(=O)Nc5cc(nn5-c5ccc(OCCN6CCOCC6)cc5)C(C)(C)C)c5ccccc45)n3)ccc2[nH]1
Show InChI InChI=1S/C42H44N10O4/c1-27-44-34-14-9-28(25-35(34)45-27)46-40-43-18-17-39(49-40)56-36-16-15-33(31-7-5-6-8-32(31)36)47-41(53)48-38-26-37(42(2,3)4)50-52(38)29-10-12-30(13-11-29)55-24-21-51-19-22-54-23-20-51/h5-18,25-26H,19-24H2,1-4H3,(H,44,45)(H,43,46,49)(H2,47,48,53)
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US Patent
n/an/a 36n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the l...

US Patent US9249125 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72QG
More data for this
Ligand-Target Pair