Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM205330'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM205330 (US9249125, 83) Show SMILES COc1ccc(cn1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4[nH]nc(C(=O)N5CCOCC5)c4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C40H39N11O5/c1-40(2,3)32-22-33(51(49-32)25-10-14-34(54-4)42-23-25)45-39(53)44-29-12-13-31(27-8-6-5-7-26(27)29)56-35-15-16-41-38(46-35)43-24-9-11-30-28(21-24)36(48-47-30)37(52)50-17-19-55-20-18-50/h5-16,21-23H,17-20H2,1-4H3,(H,47,48)(H,41,43,46)(H2,44,45,53)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the l...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
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