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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM247062'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM247062
PNG
(N-(2-(Dimethylamino)ethyl)-3-((4-((4-(3-(3-isoprop...)
Show SMILES COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3cc(OC)cc(c3)C(=O)NCCN(C)C)n2)c2ccccc12)C(C)C
Show InChI InChI=1S/C40H43N9O5/c1-25(2)34-24-36(49(47-34)28-11-13-29(52-5)14-12-28)45-40(51)44-33-15-16-35(32-10-8-7-9-31(32)33)54-37-17-18-42-39(46-37)43-27-21-26(22-30(23-27)53-6)38(50)41-19-20-48(3)4/h7-18,21-25H,19-20H2,1-6H3,(H,41,50)(H,42,43,46)(H2,44,45,51)
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US Patent
n/an/a 1n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...

US Patent US9701670 (2017)


BindingDB Entry DOI: 10.7270/Q2JM2CP2
More data for this
Ligand-Target Pair