Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM256535'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM256535 (US10435361, Example 34 | US9481648, 34 | US9790174...) Show SMILES COCCOCCOCCOc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(C(N)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OC)c1 Show InChI InChI=1S/C42H49N5O9/c1-42(2,3)27-21-34(40(43)48)39(52-6)36(22-27)47-41(49)46-35-11-12-37(33-10-8-7-9-32(33)35)56-29-13-14-44-38(26-29)45-28-23-30(51-5)25-31(24-28)55-20-19-54-18-17-53-16-15-50-4/h7-14,21-26H,15-20H2,1-6H3,(H2,43,48)(H,44,45)(H2,46,47,49)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Respivert Limited; Topivert Pharma Limited US Patent					Assay Description The following two assay variants can be used for determination of p38 MAPKα inhibition.Method 1The inhibitory activities of test compounds again...				US Patent US9790174 (2017) BindingDB Entry DOI: 10.7270/Q2M61NCF
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM256535 (US10435361, Example 34 | US9481648, 34 | US9790174...) Show SMILES COCCOCCOCCOc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(C(N)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OC)c1 Show InChI InChI=1S/C42H49N5O9/c1-42(2,3)27-21-34(40(43)48)39(52-6)36(22-27)47-41(49)46-35-11-12-37(33-10-8-7-9-32(33)35)56-29-13-14-44-38(26-29)45-28-23-30(51-5)25-31(24-28)55-20-19-54-18-17-53-16-15-50-4/h7-14,21-26H,15-20H2,1-6H3,(H2,43,48)(H,44,45)(H2,46,47,49)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Respivert Limited; Topivert Pharma Limited US Patent					Assay Description Method 2: This method follows the same steps as Method 1 above, but utilises a higher concentration of the p38 MAPKα protein (2.5 uL of 200 ng/...				US Patent US9481648 (2016) BindingDB Entry DOI: 10.7270/Q24F1PNH
					More data for this Ligand-Target Pair