Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM298446'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM298446 ((4-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(methyls...) Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)ccc1P(C)(O)=O Show InChI InChI=1S/C36H40N5O8PS/c1-36(2,3)22-18-28(34(48-5)29(19-22)41-51(7,45)46)40-35(42)39-27-13-14-30(26-11-9-8-10-25(26)27)49-24-16-17-37-33(21-24)38-23-12-15-32(50(6,43)44)31(20-23)47-4/h8-21,41H,1-7H3,(H,37,38)(H,43,44)(H2,39,40,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a
Oxular Acquisitions Limited US Patent					Assay Description p38 MAPKα Method 1: The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen) are evaluated indirectly...				US Patent US10941115 (2021) BindingDB Entry DOI: 10.7270/Q26D5X31
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