Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM381092'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM381092 (US9890185, Example 38(o)) Show SMILES COc1c(CC(N)=O)cc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccn(C)n3)c2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C33H35N7O4/c1-33(2,3)21-16-20(17-28(34)41)31(43-5)26(18-21)37-32(42)36-25-10-11-27(24-9-7-6-8-23(24)25)44-22-12-14-35-30(19-22)38-29-13-15-40(4)39-29/h6-16,18-19H,17H2,1-5H3,(H2,34,41)(H,35,38,39)(H2,36,37,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon					Assay Description Method 1: The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determinin...				J Med Chem 51: 5680-9 (2008) BindingDB Entry DOI: 10.7270/Q2FB558N
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