Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50059176'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50059176 (CHEMBL3393304) Show SMILES CCCc1c(cnn1-c1ccc(Cl)cc1)C(=O)Nc1cc(ccc1C)S(=O)(=O)N(C)C Show InChI InChI=1S/C22H25ClN4O3S/c1-5-6-21-19(14-24-27(21)17-10-8-16(23)9-11-17)22(28)25-20-13-18(12-7-15(20)2)31(29,30)26(3)4/h7-14H,5-6H2,1-4H3,(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant 5'-c-myc, His6-tagged p38-alpha using MK2 (46 to 400) as substrate assessed as inhibition of phosphorylation after 60...				J Med Chem 58: 278-93 (2015) Article DOI: 10.1021/jm501038s BindingDB Entry DOI: 10.7270/Q269758W
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50059176 (CHEMBL3393304) Show SMILES CCCc1c(cnn1-c1ccc(Cl)cc1)C(=O)Nc1cc(ccc1C)S(=O)(=O)N(C)C Show InChI InChI=1S/C22H25ClN4O3S/c1-5-6-21-19(14-24-27(21)17-10-8-16(23)9-11-17)22(28)25-20-13-18(12-7-15(20)2)31(29,30)26(3)4/h7-14H,5-6H2,1-4H3,(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of p38-alpha (unknown origin) by p38alpha-MBP IoC assay				J Med Chem 58: 278-93 (2015) Article DOI: 10.1021/jm501038s BindingDB Entry DOI: 10.7270/Q269758W
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50059176 (CHEMBL3393304) Show SMILES CCCc1c(cnn1-c1ccc(Cl)cc1)C(=O)Nc1cc(ccc1C)S(=O)(=O)N(C)C Show InChI InChI=1S/C22H25ClN4O3S/c1-5-6-21-19(14-24-27(21)17-10-8-16(23)9-11-17)22(28)25-20-13-18(12-7-15(20)2)31(29,30)26(3)4/h7-14H,5-6H2,1-4H3,(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant 5'-c-myc, His6-tagged p38-alpha using MSK1 as substrate assessed as inhibition of phosphorylation after 60 mins by EL...				J Med Chem 58: 278-93 (2015) Article DOI: 10.1021/jm501038s BindingDB Entry DOI: 10.7270/Q269758W
					More data for this Ligand-Target Pair