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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50114235'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50114235
PNG
(1-(5-tert-Butyl-2-methyl-2H-pyrazol-3-yl)-3-[4-(4-...)
Show SMILES Cn1nc(cc1NC(=O)Nc1ccc(Sc2ccc(O)cc2)cc1)C(C)(C)C
Show InChI InChI=1S/C21H24N4O2S/c1-21(2,3)18-13-19(25(4)24-18)23-20(27)22-14-5-9-16(10-6-14)28-17-11-7-15(26)8-12-17/h5-13,26H,1-4H3,(H2,22,23,27)
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n/an/a 35n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2

Bioorg Med Chem Lett 12: 1559-62 (2002)


BindingDB Entry DOI: 10.7270/Q2CV4H28
More data for this
Ligand-Target Pair