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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50251935'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50251935
PNG
(4-[4-(4-Fluoro-phenyl)-2-methylsulfanyl-1H-imidazo...)
Show SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(Oc2ccc(C)cc2)c1
Show InChI InChI=1S/C22H18FN3OS/c1-14-3-9-18(10-4-14)27-19-13-16(11-12-24-19)21-20(25-22(26-21)28-2)15-5-7-17(23)8-6-15/h3-13H,1-2H3,(H,25,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

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PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 33n/an/an/an/an/an/a



Eberhard-Karls-University Tuebingen

Curated by ChEMBL


Assay Description
Inhibition of p38alpha


J Med Chem 51: 4122-49 (2008)


Article DOI: 10.1021/jm701529q
BindingDB Entry DOI: 10.7270/Q2W37X67
More data for this
Ligand-Target Pair