Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50303230'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50303230 (3-amino-N-(4-(6-(2,6-dichlorophenyl)-8-methyl-7-ox...) Show SMILES Cn1c2nc(Nc3ccc(NC(=O)CCN)cc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(28.74,-40.46,;28.74,-38.92,;27.41,-38.15,;26.08,-38.92,;24.76,-38.15,;23.42,-38.92,;22.09,-38.15,;20.75,-38.93,;19.42,-38.15,;19.42,-36.61,;18.08,-35.84,;16.75,-36.61,;16.75,-38.15,;15.42,-35.84,;14.08,-36.61,;12.75,-35.84,;20.75,-35.84,;22.08,-36.6,;24.74,-36.61,;26.07,-35.84,;27.41,-36.61,;28.74,-35.84,;30.07,-36.6,;31.39,-35.83,;31.39,-34.29,;30.05,-33.53,;32.71,-33.51,;34.06,-34.28,;34.06,-35.82,;32.73,-36.59,;32.74,-38.13,;30.08,-38.15,;31.41,-38.91,)| Show InChI InChI=1S/C23H20Cl2N6O2/c1-31-21-13(11-16(22(31)33)20-17(24)3-2-4-18(20)25)12-27-23(30-21)29-15-7-5-14(6-8-15)28-19(32)9-10-26/h2-8,11-12H,9-10,26H2,1H3,(H,28,32)(H,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL					Assay Description Inhibition of human recombinant P38alpha				Bioorg Med Chem Lett 19: 6872-6 (2009) Article DOI: 10.1016/j.bmcl.2009.10.085 BindingDB Entry DOI: 10.7270/Q2R49QV4
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