Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50314779'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50314779 (CHEMBL1089457 | N-Cyclopropyl-4-methyl-3-(7-methyl...) Show SMILES Cc1ccc(cc1-c1cc2cnn(-c3ncccc3C(F)(F)F)c2n(C)c1=O)C(=O)NC1CC1 Show InChI InChI=1S/C24H20F3N5O2/c1-13-5-6-14(21(33)30-16-7-8-16)10-17(13)18-11-15-12-29-32(22(15)31(2)23(18)34)20-19(24(25,26)27)4-3-9-28-20/h3-6,9-12,16H,7-8H2,1-2H3,(H,30,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha-mediated AFT2 phosphorylation after 1 hr by HTRF assay				J Med Chem 53: 2973-85 (2010) Article DOI: 10.1021/jm100095x BindingDB Entry DOI: 10.7270/Q2FX79MD
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