Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50314783'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50314783 (CHEMBL1091927 | N-Cyclopropyl-3-(1-(2,6-difluoroph...) Show SMILES Cc1nn(-c2c(F)cccc2F)c2n(C)c(=O)c(cc12)-c1cc(ccc1C)C(=O)NC1CC1 |(5.79,-3.45,;5.32,-1.98,;6.23,-.74,;5.31,.53,;6.08,1.86,;7.58,1.93,;8.35,.57,;8.35,3.26,;7.52,4.55,;5.98,4.56,;5.31,3.21,;3.73,3.4,;3.86,.04,;2.53,.82,;2.54,2.36,;1.2,.06,;-.13,.84,;1.19,-1.48,;2.52,-2.26,;3.86,-1.5,;-.15,-2.24,;-1.48,-1.47,;-2.82,-2.23,;-2.83,-3.77,;-1.5,-4.55,;-.16,-3.78,;1.17,-4.56,;-4.15,-1.45,;-4.14,.09,;-5.48,-2.22,;-6.81,-1.44,;-8.35,-1.43,;-7.58,-.1,)| Show InChI InChI=1S/C25H22F2N4O2/c1-13-7-8-15(23(32)28-16-9-10-16)11-17(13)19-12-18-14(2)29-31(24(18)30(3)25(19)33)22-20(26)5-4-6-21(22)27/h4-8,11-12,16H,9-10H2,1-3H3,(H,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha-mediated AFT2 phosphorylation after 1 hr by HTRF assay				J Med Chem 53: 2973-85 (2010) Article DOI: 10.1021/jm100095x BindingDB Entry DOI: 10.7270/Q2FX79MD
					More data for this Ligand-Target Pair