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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50315134'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50315134
PNG
(4-(5-(1-methylpiperidin-4-yl)-3-(3-(trifluoromethy...)
Show SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C21H21F3N4/c1-28-11-7-15(8-12-28)19-18(14-5-9-25-10-6-14)20(27-26-19)16-3-2-4-17(13-16)21(22,23)24/h2-6,9-10,13,15H,7-8,11-12H2,1H3,(H,26,27)
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Article
PubMed
n/an/a 26.5n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting

Bioorg Med Chem Lett 20: 2634-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.047
BindingDB Entry DOI: 10.7270/Q21N818H
More data for this
Ligand-Target Pair