Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50315871'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315871 (CHEMBL1091265 | N-(2-(cyclohexylamino)pyridin-4-yl...) Show SMILES Fc1ccc(CN(C(=O)c2ccc3ccccc3c2)c2ccnc(NC3CCCCC3)c2)cc1 Show InChI InChI=1S/C29H28FN3O/c30-25-14-10-21(11-15-25)20-33(29(34)24-13-12-22-6-4-5-7-23(22)18-24)27-16-17-31-28(19-27)32-26-8-2-1-3-9-26/h4-7,10-19,26H,1-3,8-9,20H2,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counter				Bioorg Med Chem Lett 20: 2556-9 (2010) Article DOI: 10.1016/j.bmcl.2010.02.088 BindingDB Entry DOI: 10.7270/Q2VT1S84
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