BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50343506'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50343506 ((R)-4-(4-(4-fluorophenyl)-2-(isopropylsulfinyl)-1H...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					Assay Description Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assay				J Med Chem 54: 3283-97 (2011) Article DOI: 10.1021/jm101623p BindingDB Entry DOI: 10.7270/Q2W959H4
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50343506 ((R)-4-(4-(4-fluorophenyl)-2-(isopropylsulfinyl)-1H...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					Assay Description Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...				J Med Chem 54: 3283-97 (2011) Article DOI: 10.1021/jm101623p BindingDB Entry DOI: 10.7270/Q2W959H4
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					More data for this Ligand-Target Pair