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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50346922'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50346922
PNG
(CHEMBL1795682)
Show SMILES Cc1ccc(cc1-n1cnc(OCc2ccc(F)cc2F)c(Cl)c1=O)C(=O)NC[C@@H](O)CO |r|
Show InChI InChI=1S/C22H20ClF2N3O5/c1-12-2-3-13(20(31)26-8-16(30)9-29)6-18(12)28-11-27-21(19(23)22(28)32)33-10-14-4-5-15(24)7-17(14)25/h2-7,11,16,29-30H,8-10H2,1H3,(H,26,31)/t16-/m1/s1
PDB
MMDB

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PC cid
PC sid
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Patents

Article
PubMed
n/an/a 27n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of p38alpha kinase-dependent HSP-27 phosphorylation in human U937 cells


Bioorg Med Chem Lett 21: 3856-60 (2011)


Article DOI: 10.1016/j.bmcl.2011.05.006
BindingDB Entry DOI: 10.7270/Q2G73F2S
More data for this
Ligand-Target Pair