Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50347097'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50347097 (CHEMBL1797125) Show SMILES Cc1cc(OCc2ccccc2)c(Br)c(=O)n1-c1c(Cl)cccc1Cl |(2.07,-8.4,;.74,-9.16,;-.59,-8.39,;-1.92,-9.16,;-3.26,-8.4,;-4.59,-9.17,;-5.92,-8.4,;-5.92,-6.87,;-7.26,-6.1,;-8.59,-6.87,;-8.58,-8.42,;-7.24,-9.18,;-1.92,-10.7,;-3.25,-11.48,;-.59,-11.47,;-.59,-13.01,;.74,-10.7,;2.07,-11.48,;3.39,-10.71,;3.39,-9.17,;4.73,-11.47,;4.73,-13.02,;3.39,-13.79,;2.06,-13.02,;.73,-13.78,)| Show InChI InChI=1S/C19H14BrCl2NO2/c1-12-10-16(25-11-13-6-3-2-4-7-13)17(20)19(24)23(12)18-14(21)8-5-9-15(18)22/h2-10H,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as phosphorylation of fluorescently-labelled MK2 using Hsp27 peptide as substrate after 60 mins by fluorescence assay				Bioorg Med Chem Lett 21: 4059-65 (2011) Article DOI: 10.1016/j.bmcl.2011.04.120 BindingDB Entry DOI: 10.7270/Q25Q4WFH
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