Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50425374'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425374 (CHEMBL2316198) Show SMILES CNC(=O)CC[C@H](NC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1)C(=O)NC |r| Show InChI InChI=1S/C29H28F2N4O4/c1-32-26(36)12-11-25(29(39)33-2)35-28(38)18-6-4-16-3-5-17-13-20(8-9-21(17)27(37)22(16)14-18)34-24-10-7-19(30)15-23(24)31/h4,6-10,13-15,25,34H,3,5,11-12H2,1-2H3,(H,32,36)(H,33,39)(H,35,38)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425374 (CHEMBL2316198) Show SMILES CNC(=O)CC[C@H](NC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1)C(=O)NC |r| Show InChI InChI=1S/C29H28F2N4O4/c1-32-26(36)12-11-25(29(39)33-2)35-28(38)18-6-4-16-3-5-17-13-20(8-9-21(17)27(37)22(16)14-18)34-24-10-7-19(30)15-23(24)31/h4,6-10,13-15,25,34H,3,5,11-12H2,1-2H3,(H,32,36)(H,33,39)(H,35,38)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase in whole blood (unknown origin) assessed as lipopolysaccharide-stimulated TNF-alpha release by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair