BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 7' and Ligand = 'BDBM50507994'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 7


(Homo sapiens (Human))		BDBM50507994
PNG
(CHEMBL4582824)
Show SMILES Cc1ccc2c(ncnc2c1)C1CCN(CC1)C(=O)c1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C22H20F3N3O2/c1-14-2-7-18-19(12-14)26-13-27-20(18)15-8-10-28(11-9-15)21(29)16-3-5-17(6-4-16)30-22(23,24)25/h2-7,12-13,15H,8-11H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 210n/an/an/an/an/an/a



Bayer AG

Curated by ChEMBL


Assay Description
Inhibition of His-tagged MAP2K5 activated N-terminal GST-tagged recombinant human ERK5 (1 to 398 residues) expressed in Escherichia coli using biotin...

J Med Chem 62: 928-940 (2019)


Article DOI: 10.1021/acs.jmedchem.8b01606
BindingDB Entry DOI: 10.7270/Q2FN19H1
More data for this
Ligand-Target Pair