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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 8' and Ligand = 'BDBM50032817'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 8


(Homo sapiens (Human))		BDBM50032817
PNG
(CHEMBL3355145)
Show SMILES Cc1ccc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3)cn2)cn1
Show InChI InChI=1S/C23H20N6O2/c1-16-10-11-19(13-24-16)26-22(30)17-6-5-9-21(12-17)29-15-20(14-25-29)28-23(31)27-18-7-3-2-4-8-18/h2-15H,1H3,(H,26,30)(H2,27,28,31)
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Article
PubMed
n/an/a 138n/an/an/an/an/an/a



Translational Research Institute

Curated by ChEMBL


Assay Description
Inhibition of JNK1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assay

J Med Chem 57: 10013-30 (2014)


Article DOI: 10.1021/jm501256y
BindingDB Entry DOI: 10.7270/Q25140TS
More data for this
Ligand-Target Pair