Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 8' and Ligand = 'BDBM50194860'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50194860 (CHEMBL221745 | N-(4-(methylsulfonyl)benzyl)-4-amin...) Show SMILES CS(=O)(=O)c1ccc(CNC(=O)c2cc(N)c(C#N)c(n2)-c2cccc(O)c2)cc1 Show InChI InChI=1S/C21H18N4O4S/c1-30(28,29)16-7-5-13(6-8-16)12-24-21(27)19-10-18(23)17(11-22)20(25-19)14-3-2-4-15(26)9-14/h2-10,26H,12H2,1H3,(H2,23,25)(H,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JNK1				Eur J Med Chem 43: 604-13 (2008) Article DOI: 10.1016/j.ejmech.2007.04.020 BindingDB Entry DOI: 10.7270/Q2T43V9Z
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50194860 (CHEMBL221745 | N-(4-(methylsulfonyl)benzyl)-4-amin...) Show SMILES CS(=O)(=O)c1ccc(CNC(=O)c2cc(N)c(C#N)c(n2)-c2cccc(O)c2)cc1 Show InChI InChI=1S/C21H18N4O4S/c1-30(28,29)16-7-5-13(6-8-16)12-24-21(27)19-10-18(23)17(11-22)20(25-19)14-3-2-4-15(26)9-14/h2-10,26H,12H2,1H3,(H2,23,25)(H,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of JNK1 by ATF2 phosphorylation assay				Bioorg Med Chem Lett 16: 5723-30 (2006) Article DOI: 10.1016/j.bmcl.2006.08.097 BindingDB Entry DOI: 10.7270/Q28G8KBG
					More data for this Ligand-Target Pair