Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 8' and Ligand = 'BDBM50373194'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50373194 (CHEMBL258883) Show SMILES COC(=O)c1c(-c2ccc(CO)cc2)c2cc(Cl)ccc2c(=O)n1Cc1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C26H22ClNO6S/c1-34-26(31)24-23(18-7-3-17(15-29)4-8-18)22-13-19(27)9-12-21(22)25(30)28(24)14-16-5-10-20(11-6-16)35(2,32)33/h3-13,29H,14-15H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human JNK1 by radiometric assay				Bioorg Med Chem 16: 4715-32 (2008) Article DOI: 10.1016/j.bmc.2008.02.027 BindingDB Entry DOI: 10.7270/Q2JS9R8M
					More data for this Ligand-Target Pair