Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 11' and Ligand = 'BDBM354810'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354810 (6-(3,4-dimethoxyphenyl)-1- (1H-indazol-5-yl)-1H- i...) Show SMILES COc1ccc(cc1OC)-c1cnc2[nH]c(=O)n(-c3ccc4[nH]ncc4c3)c2n1 Show InChI InChI=1S/C20H16N6O3/c1-28-16-6-3-11(8-17(16)29-2)15-10-21-18-19(23-15)26(20(27)24-18)13-4-5-14-12(7-13)9-22-25-14/h3-10H,1-2H3,(H,22,25)(H,21,24,27)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester; Board of Regents of the University of Nebraska US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US10485800 (2019) BindingDB Entry DOI: 10.7270/Q22B91DW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354810 (6-(3,4-dimethoxyphenyl)-1- (1H-indazol-5-yl)-1H- i...) Show SMILES COc1ccc(cc1OC)-c1cnc2[nH]c(=O)n(-c3ccc4[nH]ncc4c3)c2n1 Show InChI InChI=1S/C20H16N6O3/c1-28-16-6-3-11(8-17(16)29-2)15-10-21-18-19(23-15)26(20(27)24-18)13-4-5-14-12(7-13)9-22-25-14/h3-10H,1-2H3,(H,22,25)(H,21,24,27)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US9814704 (2017) BindingDB Entry DOI: 10.7270/Q27H1MRN
					More data for this Ligand-Target Pair