Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 11' and Ligand = 'BDBM354850'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354850 (Preparation of 1-(cyclopropylmethyl)-6-(3,4,5-trim...) Show SMILES COc1cc(cc(OC)c1OC)-c1cnc2[nH]c(=S)n(CC3CC3)c2n1 Show InChI InChI=1S/C18H20N4O3S/c1-23-13-6-11(7-14(24-2)15(13)25-3)12-8-19-16-17(20-12)22(18(26)21-16)9-10-4-5-10/h6-8,10H,4-5,9H2,1-3H3,(H,19,21,26)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester; Board of Regents of the University of Nebraska US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US10485800 (2019) BindingDB Entry DOI: 10.7270/Q22B91DW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354850 (Preparation of 1-(cyclopropylmethyl)-6-(3,4,5-trim...) Show SMILES COc1cc(cc(OC)c1OC)-c1cnc2[nH]c(=S)n(CC3CC3)c2n1 Show InChI InChI=1S/C18H20N4O3S/c1-23-13-6-11(7-14(24-2)15(13)25-3)12-8-19-16-17(20-12)22(18(26)21-16)9-10-4-5-10/h6-8,10H,4-5,9H2,1-3H3,(H,19,21,26)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US9814704 (2017) BindingDB Entry DOI: 10.7270/Q27H1MRN
					More data for this Ligand-Target Pair