Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 11' and Ligand = 'BDBM354859'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354859 (Preparation of 3-pyridin-4-ylmethyl-5-(3,4,5-trime...) Show SMILES COc1cc(cc(OC)c1OC)-c1cnc2NC(=O)C(=Cc3ccncc3)c2c1 |w:20.21| Show InChI InChI=1S/C22H19N3O4/c1-27-18-10-14(11-19(28-2)20(18)29-3)15-9-16-17(8-13-4-6-23-7-5-13)22(26)25-21(16)24-12-15/h4-12H,1-3H3,(H,24,25,26)/b17-8+	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US9814704 (2017) BindingDB Entry DOI: 10.7270/Q27H1MRN
					More data for this Ligand-Target Pair