BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 12' and Ligand = 'BDBM289455'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase kinase kinase 12


(Homo sapiens (Human))		BDBM289455
PNG
(5-(1-(3-morpholino- bicyclo[1.1.1]pentan-1- yl)-2-...)
Show SMILES Nc1ncc(cc1OC(F)(F)F)-c1cn(c(n1)C1CCCO1)C12CC(C1)(C2)N1CCOCC1
Show InChI InChI=1S/C22H26F3N5O3/c23-22(24,25)33-17-8-14(9-27-18(17)26)15-10-30(19(28-15)16-2-1-5-32-16)21-11-20(12-21,13-21)29-3-6-31-7-4-29/h8-10,16H,1-7,11-13H2,(H2,26,27)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 6.70n/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK...

US Patent US10093664 (2018)


BindingDB Entry DOI: 10.7270/Q28P62KQ
More data for this
Ligand-Target Pair