Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 12' and Ligand = 'BDBM301544'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM301544 (US10131675, Example 30) Show SMILES Cc1c[nH]c2ncc(cc12)-c1nc(N2CCC3(COC3)C2)c2nc3n(CCOC3(C)C)c2n1 Show InChI InChI=1S/C24H27N7O2/c1-14-9-25-19-16(14)8-15(10-26-19)18-28-20(30-5-4-24(11-30)12-32-13-24)17-21(29-18)31-6-7-33-23(2,3)22(31)27-17/h8-10H,4-7,11-13H2,1-3H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	10.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...				US Patent US10131675 (2018) BindingDB Entry DOI: 10.7270/Q21G0P92
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