Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 5' and Ligand = 'BDBM307625'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307625 (N-(1-(2-(6-(4- cyclopropyl-4H- 1,2,4-triazol-3- yl...) Show SMILES CC(=O)NC1CCN(CC1)C(=O)c1ccc2C(=O)N(Cc2c1)c1cccc(n1)-c1nncn1C1CC1 Show InChI InChI=1S/C26H27N7O3/c1-16(34)28-19-9-11-31(12-10-19)25(35)17-5-8-21-18(13-17)14-32(26(21)36)23-4-2-3-22(29-23)24-30-27-15-33(24)20-6-7-20/h2-5,8,13,15,19-20H,6-7,9-12,14H2,1H3,(H,28,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q2125VQ8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307625 (N-(1-(2-(6-(4- cyclopropyl-4H- 1,2,4-triazol-3- yl...) Show SMILES CC(=O)NC1CCN(CC1)C(=O)c1ccc2C(=O)N(Cc2c1)c1cccc(n1)-c1nncn1C1CC1 Show InChI InChI=1S/C26H27N7O3/c1-16(34)28-19-9-11-31(12-10-19)25(35)17-5-8-21-18(13-17)14-32(26(21)36)23-4-2-3-22(29-23)24-30-27-15-33(24)20-6-7-20/h2-5,8,13,15,19-20H,6-7,9-12,14H2,1H3,(H,28,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q27P91GS
					More data for this Ligand-Target Pair