Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 5' and Ligand = 'BDBM503677'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503677 (US11034671, Example 69) Show SMILES Cc1ccc(cn1)-c1ccc2OCC3C[C@@H](C3)n3cnnc3-c3cccc(NC(=O)c2c1)n3 |r,wU:15.15,(-9.19,3.24,;-7.85,2.47,;-7.85,.93,;-6.52,.16,;-5.19,.93,;-5.19,2.47,;-6.52,3.24,;-3.85,.16,;-3.85,-1.38,;-2.52,-2.15,;-1.18,-1.38,;.15,-2.15,;1.48,-1.38,;2.82,-2.15,;3.91,-3.24,;4.99,-2.15,;3.91,-1.06,;6.82,-1.38,;8.28,-1.86,;9.19,-.61,;8.28,.64,;6.82,.16,;5.48,.93,;5.48,2.47,;4.15,3.24,;2.82,2.47,;2.82,.93,;1.48,.16,;.15,.93,;.15,2.47,;-1.18,.16,;-2.52,.93,;4.15,.16,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
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