Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 7' and Ligand = 'BDBM50187107'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 7 (Homo sapiens (Human))	BDBM50187107 (CHEMBL3822712) Show SMILES CN1CCN(CC1)C(=O)c1ccc(NC(=O)c2csc3c2nc[nH]c3=O)c(OC(C(F)(F)F)C(F)(F)F)c1 Show InChI InChI=1S/C22H19F6N5O4S/c1-32-4-6-33(7-5-32)19(36)11-2-3-13(14(8-11)37-20(21(23,24)25)22(26,27)28)31-17(34)12-9-38-16-15(12)29-10-30-18(16)35/h2-3,8-10,20H,4-7H2,1H3,(H,31,34)(H,29,30,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Co,. Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated ...				Bioorg Med Chem 24: 4206-4217 (2016) Article DOI: 10.1016/j.bmc.2016.07.006 BindingDB Entry DOI: 10.7270/Q2JM2CKQ
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