Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase kinase 1' and Ligand = 'BDBM590941'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human))	BDBM590941 (N-(8-amino-7-cyanoisoquinolin-3- yl)cyclopropaneca...) Show SMILES Nc1c(ccc2cc(NC(=O)C3CC3)ncc12)C#N Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	19.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...				Citation and Details BindingDB Entry DOI: 10.7270/Q2GF0ZFV
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human))	BDBM590941 (N-(8-amino-7-cyanoisoquinolin-3- yl)cyclopropaneca...) Show SMILES Nc1c(ccc2cc(NC(=O)C3CC3)ncc12)C#N Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00172 BindingDB Entry DOI: 10.7270/Q29G5RT0
					More data for this Ligand-Target Pair