Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase kinase 4' and Ligand = 'BDBM299485'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM299485 (6-[3-(6-methyl-2- pyridyl)-1- piperidyl]pyrido [3,...) Show SMILES Cc1cccc(n1)C1CCCN(C1)c1ccc2ncnc(N)c2n1 Show InChI InChI=1S/C18H20N6/c1-12-4-2-6-14(22-12)13-5-3-9-24(10-13)16-8-7-15-17(23-16)18(19)21-11-20-15/h2,4,6-8,11,13H,3,5,9-10H2,1H3,(H2,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research					Assay Description The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...				J Med Chem 46: 3709-27 (2003) BindingDB Entry DOI: 10.7270/Q2VH5R4B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM299485 (6-[3-(6-methyl-2- pyridyl)-1- piperidyl]pyrido [3,...) Show SMILES Cc1cccc(n1)C1CCCN(C1)c1ccc2ncnc(N)c2n1 Show InChI InChI=1S/C18H20N6/c1-12-4-2-6-14(22-12)13-5-3-9-24(10-13)16-8-7-15-17(23-16)18(19)21-11-20-15/h2,4,6-8,11,13H,3,5,9-10H2,1H3,(H2,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...				US Patent US9592235 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JKX
					More data for this Ligand-Target Pair