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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase kinase 4' and Ligand = 'BDBM50122725'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase kinase kinase kinase 4


(Homo sapiens (Human))
BDBM50122725
PNG
(CHEMBL3623131)
Show SMILES Nc1ncc(C(=O)NC2CC(O)C2)c2ccc(cc12)-c1cccc(F)c1 |(-1.33,2.77,;-1.33,1.54,;-2.68,.77,;-2.68,-.77,;-1.33,-1.54,;-1.33,-3.08,;-.26,-3.69,;-2.66,-3.85,;-2.65,-5.4,;-3.73,-6.44,;-2.64,-7.52,;-2.63,-8.75,;-1.55,-6.43,;,-.77,;1.33,-1.54,;2.66,-.77,;2.66,.77,;1.33,1.54,;,.77,;4,1.54,;5.33,.77,;6.66,1.53,;6.67,3.07,;5.33,3.85,;5.34,5.08,;4,3.08,)|
Show InChI InChI=1S/C20H18FN3O2/c21-13-3-1-2-11(6-13)12-4-5-16-17(7-12)19(22)23-10-18(16)20(26)24-14-8-15(25)9-14/h1-7,10,14-15,25H,8-9H2,(H2,22,23)(H,24,26)
PDB
MMDB

NCI pathway
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KEGG

UniProtKB/SwissProt

B.MOAD
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CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 41n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of MAP4K4 (unknown origin) by Z'LYTE assay


ACS Med Chem Lett 6: 913-8 (2015)


BindingDB Entry DOI: 10.7270/Q2M32XJB
More data for this
Ligand-Target Pair