Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human)) | BDBM395252 ((4aS,5aS or 4aR,5aR)-3-(Phenylamino)-2-(pyridin-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE... | Bioorg Med Chem Lett 19: 3674-8 (2009) BindingDB Entry DOI: 10.7270/Q2NZ89ZG | |||||||||||
More data for this Ligand-Target Pair |