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Found 1 hit Enz. Inhib. hit(s) with Target = 'Monoacylglycerol lipase ABHD6' and Ligand = 'BDBM444458'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Monoacylglycerol lipase ABHD6


(Homo sapiens (Human))		BDBM444458
PNG
(US10662159, Example 46)
Show SMILES CN(C)CCOc1ccc2CN(Cc2c1)C(=O)OC(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C16H18F6N2O3/c1-23(2)5-6-26-12-4-3-10-8-24(9-11(10)7-12)14(25)27-13(15(17,18)19)16(20,21)22/h3-4,7,13H,5-6,8-9H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



MAKSCIENTIFIC, LLC

US Patent


Assay Description
ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...

US Patent US10662159 (2020)


BindingDB Entry DOI: 10.7270/Q2RB77NZ
More data for this
Ligand-Target Pair