Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Monoacylglycerol lipase ABHD6' and Ligand = 'BDBM444461'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444461 (US10662159, Example 49) Show SMILES FC(F)(F)C(OC(=O)N1Cc2ccc(OCCN3CCCC3)cc2C1)C(F)(F)F Show InChI InChI=1S/C18H20F6N2O3/c19-17(20,21)15(18(22,23)24)29-16(27)26-10-12-3-4-14(9-13(12)11-26)28-8-7-25-5-1-2-6-25/h3-4,9,15H,1-2,5-8,10-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair