Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Monoacylglycerol lipase ABHD6' and Ligand = 'BDBM444469'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444469 (US10662159, Example 59) Show SMILES Fc1cccc(OC2CCC3(CN(C3)C(=O)OC(C(F)(F)F)C(F)(F)F)C2)c1 Show InChI InChI=1S/C17H16F7NO3/c18-10-2-1-3-11(6-10)27-12-4-5-15(7-12)8-25(9-15)14(26)28-13(16(19,20)21)17(22,23)24/h1-3,6,12-13H,4-5,7-9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
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