BindingDB PrimarySearch

Found 4 hits Enz. Inhib. hit(s) with Target = 'Monoglyceride lipase' and Ligand = 'BDBM50307083'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM50307083 (4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carb...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128763 BindingDB Entry DOI: 10.7270/Q2SQ94FW
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50307083 (4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carb...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116698 BindingDB Entry DOI: 10.7270/Q22B933P
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Mus musculus (mouse))	BDBM50307083 (4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAGL in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50307083 (4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carb...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	205	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 mins				J Med Chem 63: 5783-5796 (2020) Article DOI: 10.1021/acs.jmedchem.9b02137 BindingDB Entry DOI: 10.7270/Q2GQ7288
China Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair