Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Monoglyceride lipase' and Ligand = 'BDBM581678'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM581678 ((2s,4S)-N-((1s,3S)-3-(4-Isopropylphenyl)cyclobutyl...) Show SMILES CC(C)c1ccc(cc1)[C@@H]1C[C@@H](C1)N(C)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:17.18,11.14,9.9,wD:19.21,$;;;;;;;;;;;;;;;;;;;;;;;;;HN$,(9.21,2.4,;7.87,3.17,;7.87,4.71,;6.54,2.4,;6.54,.86,;5.2,.09,;3.87,.86,;3.87,2.4,;5.2,3.17,;2.54,.09,;1.05,.49,;.65,-1,;2.14,-1.4,;-.68,-1.77,;-.68,-3.31,;-2.02,-1,;-2.02,.54,;-3.35,-1.77,;-3.75,-3.26,;-5.24,-2.86,;-4.84,-1.37,;-5.4,-4.39,;-6.9,-4.71,;-7.67,-3.38,;-9.21,-3.22,;-6.64,-2.23,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL expressed in HeLa cells using [glycerol-1, 3-3H]-oleoyl glycerol as substrate incubated for 1 hr				Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00019 BindingDB Entry DOI: 10.7270/Q2NZ8CJX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581678 ((2s,4S)-N-((1s,3S)-3-(4-Isopropylphenyl)cyclobutyl...) Show SMILES CC(C)c1ccc(cc1)[C@@H]1C[C@@H](C1)N(C)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:17.18,11.14,9.9,wD:19.21,$;;;;;;;;;;;;;;;;;;;;;;;;;HN$,(9.21,2.4,;7.87,3.17,;7.87,4.71,;6.54,2.4,;6.54,.86,;5.2,.09,;3.87,.86,;3.87,2.4,;5.2,3.17,;2.54,.09,;1.05,.49,;.65,-1,;2.14,-1.4,;-.68,-1.77,;-.68,-3.31,;-2.02,-1,;-2.02,.54,;-3.35,-1.77,;-3.75,-3.26,;-5.24,-2.86,;-4.84,-1.37,;-5.4,-4.39,;-6.9,-4.71,;-7.67,-3.38,;-9.21,-3.22,;-6.64,-2.23,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	0.0400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2HM5D9C
					More data for this Ligand-Target Pair