Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM144360'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM144360 (US8969358, 111) Show SMILES CO[C@]12CC[C@@]3(C[C@@H]1CNC(=O)[C@H](Cc1ccccc1)NC(C)=O)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 |r,TLB:8:7:34.33:4.3| Show InChI InChI=1S/C35H43N3O5/c1-21(39)37-26(16-22-6-4-3-5-7-22)31(41)36-19-25-18-33-12-13-35(25,42-2)32-34(33)14-15-38(20-23-8-9-23)28(33)17-24-10-11-27(40)30(43-32)29(24)34/h3-7,10-11,23,25-26,28,32,40H,8-9,12-20H2,1-2H3,(H,36,41)(H,37,39)/t25-,26+,28-,32-,33-,34+,35-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.360	-58.4	n/a	n/a	n/a	n/a	n/a	7.4	50
Purdue Pharma L.P. US Patent					Assay Description u-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for u-opioid receptors used 0.3 nM [3H]-diprenorphine (Perki...				US Patent US8969358 (2015) BindingDB Entry DOI: 10.7270/Q2DF6PXG
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