Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM309428'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM309428 (US9656961, Example 00148) Show SMILES C[C@H]1C2N(CC3CC3)CC[C@]1(C)c1cc(ccc1C2=O)C(N)=O |r,TLB:13:12:3.9.8:1,4:3:12.17.18:1,THB:19:18:3.9.8:1| Show InChI InChI=1S/C19H24N2O2/c1-11-16-17(22)14-6-5-13(18(20)23)9-15(14)19(11,2)7-8-21(16)10-12-3-4-12/h5-6,9,11-12,16H,3-4,7-8,10H2,1-2H3,(H2,20,23)/t11-,16?,19-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ALKERMES PHARMA IRELAND LIMITED US Patent					Assay Description The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...				US Patent US9656961 (2017) BindingDB Entry DOI: 10.7270/Q2PR7Z13
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM309428 (US9656961, Example 00148) Show SMILES C[C@H]1C2N(CC3CC3)CC[C@]1(C)c1cc(ccc1C2=O)C(N)=O |r,TLB:13:12:3.9.8:1,4:3:12.17.18:1,THB:19:18:3.9.8:1| Show InChI InChI=1S/C19H24N2O2/c1-11-16-17(22)14-6-5-13(18(20)23)9-15(14)19(11,2)7-8-21(16)10-12-3-4-12/h5-6,9,11-12,16H,3-4,7-8,10H2,1-2H3,(H2,20,23)/t11-,16?,19-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
ALKERMES PHARMA IRELAND LIMITED US Patent					Assay Description The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...				US Patent US9656961 (2017) BindingDB Entry DOI: 10.7270/Q2PR7Z13
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM309428 (US9656961, Example 00148) Show SMILES C[C@H]1C2N(CC3CC3)CC[C@]1(C)c1cc(ccc1C2=O)C(N)=O |r,TLB:13:12:3.9.8:1,4:3:12.17.18:1,THB:19:18:3.9.8:1| Show InChI InChI=1S/C19H24N2O2/c1-11-16-17(22)14-6-5-13(18(20)23)9-15(14)19(11,2)7-8-21(16)10-12-3-4-12/h5-6,9,11-12,16H,3-4,7-8,10H2,1-2H3,(H2,20,23)/t11-,16?,19-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
ALKERMES PHARMA IRELAND LIMITED US Patent					Assay Description The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...				US Patent US9656961 (2017) BindingDB Entry DOI: 10.7270/Q2PR7Z13
					More data for this Ligand-Target Pair