BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM438945'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM438945 (US10604489, Compound 106 \| US11180455, Compound 10...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The Ki (binding affinity) for μ-receptor was determined with a previously described method using a competitive displacement assay (Neumeyer et a...				Citation and Details BindingDB Entry DOI: 10.7270/Q24J0J91
TBA					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM438945 (US10604489, Compound 106 \| US11180455, Compound 10...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alkermes, Inc. US Patent					Assay Description Membrane protein from CHO (Chinese Hamster Ovarian) cells that stably expressed one type of the cloned human opioid receptor were incubated with 12 d...				US Patent US10604489 (2020) BindingDB Entry DOI: 10.7270/Q2RN3BWX
Alkermes, Inc. US Patent					More data for this Ligand-Target Pair