BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50001089'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001089 (13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assay				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
G.D. Searle and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001089 (13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Dissociation rate constant of compound for mutant T46S Escherichia coli dihydrofolate reductase				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
G.D. Searle and Company Curated by ChEMBL					More data for this Ligand-Target Pair